Sparteine d-isomer
(+)-Sparteine
CAS: 492-08-0
Molecular Formula: C15H26N2
Sparteine d-isomer - Names and Identifiers
| Name | (+)-Sparteine |
| Synonyms | d-Sparteine PACHYCARPINE (+)-Sparteine (+)-SPARTEINE Sparteine d-isomer (1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane |
| CAS | 492-08-0 |
| EINECS | 805-899-0 |
| InChIKey | SLRCCWJSBJZJBV-TUVASFSCSA-N |
Sparteine d-isomer - Physico-chemical Properties
| Molecular Formula | C15H26N2 |
| Molar Mass | 234.38 |
| Density | 1.08 |
| Melting Point | 201℃ |
| Boling Point | 174°C/8mmHg(lit.) |
| Solubility | Chloroform (slightly), Ethanol |
| Appearance | Liquid |
| Color | Colourless to Light Yellow Thick |
| Maximum wavelength(λmax) | ['202nm(CH3CN)(lit.)'] |
| pKa | 10.08±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n/D1.527 |
| MDL | MFCD00869353 |
| In vitro study | (+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay. |
Sparteine d-isomer - Risk and Safety
| RTECS | RT0620000 |
| Toxicity | LD50 scu-mus: 90 mg/kg FATOAO 21(5),46,58 |
Sparteine d-isomer - Reference Information
| biological activity | ( )-Sparteine is a natural alkaloid that acts as a ganglion blocker. In nerve cells,( )-Sparteine competitively inhibits nicotinic acetylcholine receptor (nACh receptor) activity. |
| Target | AChR |
| Use | for content determination/identification/pharmacological experiments |
Last Update：2024-04-10 22:29:15
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Multiple SpecificationsSpot supply
Product Name: (+)-Sparteine Visit Supplier Webpage Request for quotationCAS: 492-08-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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